Transpulmonary passage of99mTc macroaggregated albumin in healthy humans at rest and during maximal exercise

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Transpulmonary passage of 99mTc macroaggregated albumin in healthy humans at rest and during maximal exercise.

We have demonstrated that 50-mum-diameter arteriovenous pathways exist in isolated, healthy human and baboon lungs, ventilated and perfused under physiological pressures. These findings have been confirmed and extended by demonstrating the passage of 25-microm microspheres through the lungs of exercising dogs, but not at rest. Determination of blood flow through these large-diameter intrapulmon...

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Transpulmonary passage of Tc macroaggregated albumin in healthy humans at rest and during maximal exercise

Lovering AT, Haverkamp HC, Romer LM, Hokanson JS, Eldridge MW. Transpulmonary passage of Tc macroaggregated albumin in healthy humans at rest and during maximal exercise. J Appl Physiol 106: 1986–1992, 2009. First published April 16, 2009; doi:10.1152/japplphysiol.01357.2007.—We have demonstrated that 50m-diameter arteriovenous pathways exist in isolated, healthy human and baboon lungs, ventila...

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Hypoxia and Exercise Increase the Transpulmonary Passage of 99mTc-Labeled Albumin Particles in Humans

Intrapulmonary arteriovenous anastomoses (IPAVs) are large diameter connections that allow blood to bypass the lung capillaries and may provide a route for right-to-left embolus transmission. These anastomoses are recruited by exercise and catecholamines and hypoxia. Yet, whether IPAVs are recruited via direct, oxygen sensitive regulatory mechanisms or indirect effects secondary to redistributi...

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Short-term hypoxic exposure at rest and during exercise reduces lung water in healthy humans.

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ژورنال

عنوان ژورنال: Journal of Applied Physiology

سال: 2009

ISSN: 8750-7587,1522-1601

DOI: 10.1152/japplphysiol.01357.2007